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                                                                                        	         	                                                      	  	          
  	                                       	        T k   +   7 T   uë  v§  v±  vÙ  y×  }s  ‚·F“	« ± uv ¾Ðs2	Ø	ê	˜
a‚Æõ
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,¡´²Cõ yþ 
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tªh=K­öç<ÅHÉ ¯ws/4 ŸE½OÖ?/›ÿ	hø’Cmy
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s³Œš†11¾Ï O¸Ö?,/yÌ.�	þy†šô3nÃ›ú‡ ‰A	«÷ 7	¶«±
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a)+V²º©
ålŠ« Z#Š¦úŸ¢çWþ•\ª•©O.'+éAk´êhHišú¡�‚b«:ªVtö…ÙÂ†¥—‡WmþèåL=AÎ<ð*2ª<†¬‰¦‚§¦ª£Õ8–k§jj�ª‘X…ULÌi‰VeHdÂ}¦BQX�ØQ_(V‹57Íç¶®(ê’¶ÆÍ°ã…ÕEVjZ¥„ÐS‹HJ‰RD5aÄ,ö»¸AD±ZŽ¶¡\kâ©¼¡)OÑF s:±½1«¦hQ4R\uƒA¾äK�;}÷ß}Ôèš9  !<AdditionalSequenceProperties><UpstreamStickiness>0</UpstreamStickiness><DownstreamStickiness>0</DownstreamStickiness><UpstreamModification>FivePrimePhosphorylated</UpstreamModification><DownstreamModification>FivePrimePhosphorylated</DownstreamModification></AdditionalSequenceProperties>
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<SequenceClass>UNA</SequenceClass>
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</Notes>
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<SequenceClass>UNA</SequenceClass>
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</Notes>
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  F<?xml version="1.0"?><Features nextValidID="9"><Feature recentID="0" name="6xHis" directionality="1" translationMW="840.86" type="CDS" allowSegmentOverlaps="0" consecutiveTranslationNumbering="1" maxRunOn="7007" maxFusedRunOn="7007" detectionMode="exactProteinMatch"><Segment range="6963-6980" color="#cc99b2" type="standard" translated="1"/><Q name="codon_start"><V int="1"/></Q><Q name="product"><V text="&lt;html&gt;&lt;body&gt;6xHis affinity tag&lt;/body&gt;&lt;/html&gt;"/></Q><Q name="transl_table"><V int="1"/></Q><Q name="translation"><V text="HHHHHH"/></Q></Feature><Feature recentID="1" name="AmpR promoter" directionality="1" type="promoter" allowSegmentOverlaps="0" consecutiveTranslationNumbering="1"><Segment range="780-884" color="#ffffff" type="standard"/><Q name="gene"><V text="&lt;html&gt;&lt;body&gt;&lt;i&gt;bla&lt;/i&gt;&lt;/body&gt;&lt;/html&gt;"/></Q></Feature><Feature recentID="2" name="ori" directionality="1" type="rep_origin" allowSegmentOverlaps="0" consecutiveTranslationNumbering="1"><Segment range="1916-2504" color="#ffff00" type="standard"/><Q name="direction"><V text="RIGHT"/></Q><Q name="note"><V text="&lt;html&gt;&lt;body&gt;high-copy-number ColE1/pMB1/pBR322/pUC origin of replication&lt;/body&gt;&lt;/html&gt;"/></Q></Feature><Feature recentID="3" name="AmpR" directionality="1" translationMW="31558.16" type="CDS" allowSegmentOverlaps="0" cleavageArrows="953" consecutiveTranslationNumbering="1" hitsStopCodon="1" detectionMode="exactProteinMatch"><Segment name="signal sequence" range="885-953" color="#ccffcc" type="standard" translated="1"/><Segment range="954-1745" color="#ccffcc" type="standard" translated="1"/><Q name="codon_start"><V int="1"/></Q><Q name="gene"><V text="&lt;html&gt;&lt;body&gt;&lt;i&gt;bla&lt;/i&gt;&lt;/body&gt;&lt;/html&gt;"/></Q><Q name="note"><V text="&lt;html&gt;&lt;body&gt;confers resistance to ampicillin, carbenicillin, and related antibiotics&lt;/body&gt;&lt;/html&gt;"/></Q><Q name="product"><V text="&lt;html&gt;&lt;body&gt;Î²-lactamase&lt;/body&gt;&lt;/html&gt;"/></Q><Q name="transl_table"><V int="1"/></Q><Q name="translation"><V text="MSIQHFRVALIPFFAAFCLPVFA,HPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRIDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW*"/></Q></Feature><Feature recentID="4" name="repB" directionality="2" translationMW="39773.56" type="CDS" swappedSegmentNumbering="1" allowSegmentOverlaps="0" readingFrame="-1" consecutiveTranslationNumbering="1" hitsStopCodon="1"><Segment range="4837-5841" color="#993366" type="standard" translated="1"/><Q name="codon_start"><V int="1"/></Q><Q name="db_xref"><V text="22652809" predef="GI"/></Q><Q name="gene"><V text="repB"/></Q><Q name="note"><V text="&lt;html&gt;&lt;body&gt;from &lt;i&gt;Enterococcus faecalis&lt;/i&gt; plasmid pAMÎ±1&lt;/body&gt;&lt;/html&gt;"/></Q><Q name="product"><V text="RepB replication protein"/></Q><Q name="protein_id"><V text="AAN03827.1"/></Q><Q name="transl_table"><V int="1"/></Q><Q name="translation"><V text="MGVSFNIMCPNSSIYSDEKSRVLVDKTKSGKVRPWREKKIANVDYFELLHILEFKKAERVKDCAEILEYKQNRETGERKLYRVWFCKSRLCPMCNWRRAMKHGIQSQKVVAEVIKQKPTVRWLFLTLTVKNVYDGEELNKSLSDMAQGFRRMMQYKKINKNLVGFMRATEVTINNKDNSYNQHMHVLVCVEPTYFKNTENYVNQKQWIQFWKKAMKLDYDPNVKVQMIRPKNKYKSDIQSAIDETAKYPVKDTDFMTDDEEKNLKRLSDLEEGLHRKRLISYGGLLKEIHKKLNLDDTEEGDLIHTDDDEKADEDGFSIIAMWNWERKNYFIKE*"/></Q></Feature><Feature recentID="5" name="p43  Promoter" directionality="1" type="misc_feature" allowSegmentOverlaps="0" consecutiveTranslationNumbering="1"><Segment range="6260-6564" color="#ffffff" type="standard"/></Feature><Feature recentID="6" name="Apr sp+pro" directionality="1" translationMW="12145.99" type="CDS" allowSegmentOverlaps="0" consecutiveTranslationNumbering="1" maxRunOn="7007" maxFusedRunOn="7007"><Segment range="6597-6929" color="#ffcc00" type="standard" translated="1"/><Q name="codon_start"><V int="1"/></Q><Q name="transl_table"><V int="1"/></Q><Q name="translation"><V text="MKKPLGKIVASTALLISVAFSSSIASAAEEAKEKYLIGFNEQEAVSEFVEQVEANDEVAILSEEEEVEIELLHEFETIPVLSVELSPEDVDALELDPAISYIEEDAEVTTM"/></Q></Feature><Feature recentID="7" name="NeoR/KanR" directionality="2" type="misc_feature" swappedSegmentNumbering="1" allowSegmentOverlaps="0" readingFrame="-1" consecutiveTranslationNumbering="1"><Segment range="3907-4677" color="#ccffcc" type="standard"/></Feature><Feature recentID="8" name="MCS" type="misc_feature" allowSegmentOverlaps="0" consecutiveTranslationNumbering="1"><Segment range="6933-6962" color="#ffff00" type="standard"/></Feature></Features>
   —<?xml version="1.0"?><Primers nextValidID="0"><HybridizationParams minContinuousMatchLen="10" allowMismatch="1" minMeltingTemperature="40"/></Primers>
  �<Notes>
<UUID>a8e9be71-e094-40c2-a99e-ffc2d322ed10</UUID>
<Type>Synthetic</Type>
<ConfirmedExperimentally>0</ConfirmedExperimentally>
<CustomMapLabel>pBE2R</CustomMapLabel>
<UseCustomMapLabel>1</UseCustomMapLabel>
<Created UTC="9:9:35">2018.1.2</Created>
<LastModified UTC="2:2:47">2025.7.8</LastModified>
<SequenceClass>UNA</SequenceClass>
<TransformedInto>unspecified</TransformedInto>
</Notes>
  Y      K         
?????                                                                                                       ÿ d      DO  d              E              ÿÿÿÿYô? P                                                                                                                                                              ­<StrandColors><TopStrand><ColorRange range="6929..6931" colors="blue"/></TopStrand><BottomStrand><ColorRange range="6929..6931" colors="blue"/></BottomStrand></StrandColors>   3<?xml version="1.0"?><EnzymeVisibilities vals=""/>
   )<?xml version="1.0"?><CustomEnzymeSets/>
